Description

Spiro[2.5]Octan-5-Amine Hydrochloride is a high-purity, specialized organic building block featuring a unique spirocyclic structure. This compound is valued for its role as a key chiral intermediate in advanced pharmaceutical synthesis and fine chemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its spirocyclic scaffold for unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties due to its rigid structure.
• Academic & Industrial R&D: Employed in methodological chemistry research for studying ring strain, reaction mechanisms, and new synthetic pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring complex, stereodefined amine derivatives.

Basic Information

Product Name	Spiro[2.5]Octan-5-Amine Hydrochloride
CAS No.	1228449-89-5
Molecular Formula	C8H16ClN
Molecular Weight	161.67 g/mol
Synonyms	5-Aminospiro[2.5]octane hydrochloride; Spiro[2.5]octan-5-amine, hydrochloride; 5-Azaspiro[2.5]octane, 5-amino-, hydrochloride (8CI); 1-Azaspiro[2.5]octan-5-amine hydrochloride; 5-Amino-1-azaspiro[2.5]octane hydrochloride; Spirocyclic amine hydrochloride; 5-Aminospirooctane HCl
EINECS	Contact for details

Quality Control

Our Spiro[2.5]Octan-5-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via NMR and IR spectroscopy. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.