Description

3-(1H-Pyrrol-1-Yl)-5-(Trifluoromethyl)-1-Benzothiophene-2-Carboxylic Acid is a high-value, multifunctional heterocyclic building block designed for advanced chemical synthesis. This compound is essential for research and development in pharmaceutical and agrochemical discovery due to its unique structural features, including the benzothiophene core, trifluoromethyl group, and pyrrole substituent. It is primarily targeted at medicinal chemists and process development scientists working on novel active ingredients, where it serves as a key intermediate for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in oncology, CNS, and anti-inflammatory research pipelines.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the stability and bioactivity of the benzothiophene scaffold.
• Material Science Precursor: Serves as a monomer or functional additive in the development of advanced organic electronic materials, such as OLEDs or semiconductors.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	3-(1H-Pyrrol-1-Yl)-5-(Trifluoromethyl)-1-Benzothiophene-2-Carboxylic Acid
CAS No.	1227955-00-1
Molecular Formula	C14H8F3NO2S
Molecular Weight	311.28 g/mol
Synonyms	5-(Trifluoromethyl)-3-(1H-pyrrol-1-yl)thieno[2,3-c]pyridine-7-carboxylic acid (alternative ring numbering); 3-(1H-Pyrrol-1-yl)-5-(trifluoromethyl)benzo[b]thiophene-2-carboxylic acid; 3-Pyrrol-1-yl-5-trifluoromethyl-1-benzothiophene-2-carboxylic acid; 1227955-00-1; Benzothiophene-2-carboxylic acid, 3-(1H-pyrrol-1-yl)-5-(trifluoromethyl)-; 3-(1H-Pyrrol-1-yl)-5-(trifluoromethyl)benzo[b]thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of 3-(1H-Pyrrol-1-Yl)-5-(Trifluoromethyl)-1-Benzothiophene-2-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for your critical R&D and scale-up processes. Certificates of Analysis (COA) detailing batch-specific results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is compatible with strong acid/organic solvent environments but should be handled with appropriate precautions. Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.