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6-Iodo-8-Methylimidazo[1,2-A]-Pyridine-2-Carboxylic Acid CAS NO 1227954-99-5


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CAS No.:1227954-99-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Iodo-8-Methylimidazo[1,2-A]-Pyridine-2-Carboxylic Acid is a high-value, halogenated heterocyclic building block of significant interest in modern synthetic chemistry. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process R&D, and the synthesis of targeted small molecule libraries.

Application

  • Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for targeting various disease pathways.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its reactive iodine moiety and imidazopyridine core.
  • Chemical Synthesis Building Block: Enables cross-coupling reactions (e.g., Suzuki, Sonogashira) for the introduction of complex substituents, facilitating the synthesis of diverse chemical entities.
  • Agrochemical Research: Serves as a potential intermediate in the discovery of new crop protection agents and pesticides.
  • Material Science Exploration: Investigated for the preparation of specialized organic ligands or functional materials.

Basic Information

Product Name 6-Iodo-8-Methylimidazo[1,2-A]-Pyridine-2-Carboxylic Acid
CAS No. 1227954-99-5
Molecular Formula C9H7IN2O2
Molecular Weight 302.07 g/mol
Synonyms 8-Methyl-6-iodoimidazo[1,2-a]pyridine-2-carboxylic acid; 6-Iodo-8-methyl-2-imidazo[1,2-a]pyridinecarboxylic acid; Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-iodo-8-methyl-; 1227954-99-5; AI3-63500; ZINC000103046757; AKOS040759583; BDBM50389371
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Quality Control

Our 6-Iodo-8-Methylimidazo[1,2-A]-Pyridine-2-Carboxylic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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