Description

n-(4-Fluorophenyl)-N'-[2-Methyl-6-(Trifluoromethyl)Pyridin-3-Yl]Urea is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is critical for medicinal chemists seeking to develop novel small molecule therapeutics, particularly in kinase inhibitor programs. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery projects.
• Agrochemical Development: Potential intermediate in the research and synthesis of advanced crop protection agents and herbicides.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study biological pathways and protein functions.
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	n-(4-Fluorophenyl)-N'-[2-Methyl-6-(Trifluoromethyl)Pyridin-3-Yl]Urea
CAS No.	1227954-98-4
Molecular Formula	C14H11F4N3O
Molecular Weight	313.25 g/mol
Synonyms	1-(4-Fluorophenyl)-3-[2-methyl-6-(trifluoromethyl)pyridin-3-yl]urea; N-(4-Fluorophenyl)-N'-[2-methyl-6-(trifluoromethyl)-3-pyridinyl]urea; Urea, N-(4-fluorophenyl)-N'-[2-methyl-6-(trifluoromethyl)-3-pyridinyl]-; 1227954-98-4; 4-Fluoro-N-((2-methyl-6-(trifluoromethyl)pyridin-3-yl)carbamoyl)aniline
EINECS	Contact for details

Quality Control

Our n-(4-Fluorophenyl)-N'-[2-Methyl-6-(Trifluoromethyl)Pyridin-3-Yl]Urea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.