Description

4-Iodo-5-Trifluoromethyl-Pyridin-2-Ol is a high-value, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both iodine and a trifluoromethyl group on the pyridine ring, makes it an indispensable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for targeted therapies and fluorinated drug molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Serves as a building block for advanced organic electronic materials, such as ligands for catalysts and components for organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Versatile reagent for cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution, enabling the introduction of the pyridinyl moiety into complex architectures.
• Life Science Research: Employed as a biochemical probe or a tagged molecule in medicinal chemistry for structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Iodo-5-Trifluoromethyl-Pyridin-2-Ol
CAS No.	1227601-04-8
Molecular Formula	C6H3F3INO
Molecular Weight	288.99 g/mol
Synonyms	2-Hydroxy-4-iodo-5-(trifluoromethyl)pyridine; 4-Iodo-5-(trifluoromethyl)pyridin-2-ol; 5-Trifluoromethyl-4-iodopyridin-2-ol; 4-Iodo-5-trifluoromethyl-2-pyridinol; 2-Pyridinol, 4-iodo-5-(trifluoromethyl)-; 1227601-04-8
EINECS	Contact for details

Quality Control

Our production of 4-Iodo-5-Trifluoromethyl-Pyridin-2-Ol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.