Description

1-(1-Cyclopropyl-1H-Imidazol-5-Yl)Methanamine (Saltdata: 2HCl) is a high-purity, advanced pharmaceutical intermediate characterized by its distinct imidazole-cyclopropyl amine structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, or oncology.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Bioconjugation & Probe Development: The primary amine functionality allows for conjugation to fluorescent tags, biotin, or other molecules for creating biochemical probes.
• Ligand Synthesis for Catalysis: Can be utilized to synthesize specialized ligands for transition metal catalysts used in asymmetric synthesis.
• Agrochemical Intermediate: Potential use in the research and development of new crop protection agents and pesticides.

Basic Information

Product Name	1-(1-Cyclopropyl-1H-Imidazol-5-Yl)Methanamine (Saltdata: 2HCl)
CAS No.	1227465-77-1
Molecular Formula	C7H11N3 • 2HCl
Molecular Weight	226.10 g/mol (as dihydrochloride salt)
Synonyms	1-(1-Cyclopropyl-1H-imidazol-5-yl)methanamine dihydrochloride; (1-Cyclopropyl-1H-imidazol-5-yl)methanamine hydrochloride (1:2); 5-(Aminomethyl)-1-cyclopropyl-1H-imidazole dihydrochloride; 1-Cyclopropyl-1H-imidazole-5-methanamine dihydrochloride; 1-Cyclopropyl-5-(aminomethyl)imidazole dihydrochloride; 1-Cyclopropyl-5-imidazolemethanamine dihydrochloride; CPIMA dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(1-Cyclopropyl-1H-Imidazol-5-Yl)Methanamine dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.