Description

tert-Butyl 3-Hydrazinylpiperidine-1-Carboxylate Oxalate is a high-purity, protected piperidine-hydrazine derivative that serves as a critical building block in modern pharmaceutical synthesis. This compound is essential for research and development chemists seeking to construct complex nitrogen-containing heterocycles and active pharmaceutical ingredients (APIs). It is primarily utilized in the pharmaceutical and agrochemical industries for the development of novel therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of piperidine-based drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides that require a functionalized piperidine scaffold.
• Chemical Biology & Proteomics: Employed as a linker or reagent in bioconjugation chemistry and activity-based protein profiling (ABPP).
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and functional materials.
• Academic & Contract Research: Serves as a versatile starting material for method development and library synthesis in medicinal chemistry.

Basic Information

Product Name	tert-Butyl 3-Hydrazinylpiperidine-1-Carboxylate Oxalate
CAS No.	1226815-22-0
Molecular Formula	C11H21N3O2 • C2H2O4
Molecular Weight	331.34 g/mol
Synonyms	1-Boc-3-hydrazinopiperidine oxalate; tert-Butyl 3-hydrazinyl-1-piperidinecarboxylate oxalate; 3-Hydrazino-1-piperidinecarboxylic acid tert-butyl ester oxalate; 1-(tert-Butoxycarbonyl)-3-hydrazinopiperidine oxalic acid salt; 3-Hydrazinylpiperidine-1-carboxylic acid tert-butyl ester oxalate; 1-Boc-3-hydrazinopiperidine oxalic acid salt; Boc-3-hydrazinopiperidine oxalate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Hydrazinylpiperidine-1-Carboxylate Oxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all relevant specifications. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.