Description

n-Hydroxy-2,3:5,6-Bis-o-(1-methylethylidene)-α-L-glucofuranosylamine is a sophisticated, high-purity carbohydrate derivative featuring a protected glucofuranose core with a reactive N-hydroxyamine functional group. This compound matters for its role as a versatile chiral intermediate and building block in advanced organic synthesis, enabling the development of complex molecules with precise stereochemistry. It is primarily needed by research institutions and industrial R&D teams in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in drug discovery, catalyst development, and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for nucleoside analogs and glycosidase inhibitors.
• Glycochemistry Research: Used as a protected glycosyl donor or acceptor in the synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics for biological studies.
• Catalyst and Ligand Synthesis: Acts as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Agrochemical Development: Employed in the design and synthesis of novel, biologically active compounds for crop protection and plant growth regulation.
• Chemical Biology Probes: Utilized to develop molecular probes for studying carbohydrate-processing enzymes and carbohydrate-mediated biological recognition events.
• Material Science: Potential building block for creating functionalized polymers or surfaces with specific chiral or hydrophilic properties.

Basic Information

Product Name	n-Hydroxy-2,3:5,6-Bis-o-(1-methylethylidene)-α-L-glucofuranosylamine
CAS No.	1226812-51-6
Molecular Formula	C12H21NO6
Molecular Weight	275.30 g/mol
Synonyms	N-Hydroxy-2,3:5,6-di-O-isopropylidene-α-L-glucofuranosylamine; α-L-Glucofuranosylamine, N-hydroxy-2,3:5,6-bis-O-(1-methylethylidene)-; 2,3:5,6-Di-O-isopropylidene-α-L-glucofuranosylhydroxylamine; Isopropylidene-protected glucofuranosyl N-hydroxyamine; L-Glucofuranose derivative, N-hydroxy, diacetonide; (2R,3S,4R,5R)-2,3:5,6-Bis-O-(1-methylethylidene)-α-L-glucofuranosylhydroxylamine
EINECS	Contact for details

Quality Control

Our n-Hydroxy-2,3:5,6-Bis-o-(1-methylethylidene)-α-L-glucofuranosylamine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and optical rotation analysis, to verify identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Optical Rotation	[α]20/D: Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.