Description

[1,1'-Biphenyl]-3-Amine, 2'-Chloro-4-Fluoro- is a high-purity, halogenated biphenyl amine derivative serving as a critical advanced intermediate in organic synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the life sciences sector for applications such as drug discovery and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated biphenyl structure.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the biphenyl amine moiety into more complex molecular architectures.

Basic Information

Product Name	[1,1'-Biphenyl]-3-Amine, 2'-Chloro-4-Fluoro-
CAS No.	1226002-02-3
Molecular Formula	C12H9ClFN
Molecular Weight	221.66 g/mol
Synonyms	2'-Chloro-4-fluoro-[1,1'-biphenyl]-3-amine; 3-Amino-2'-chloro-4-fluorobiphenyl; 2'-Chloro-4-fluorobiphenyl-3-amine; 2-Chloro-4-fluoro-3-phenylaniline; (2'-Chloro-4'-fluorobiphenyl-3-yl)amine; 2'-Chloro-4'-fluoro-3-aminobiphenyl
EINECS	Contact for details

Quality Control

Our [1,1'-Biphenyl]-3-Amine, 2'-Chloro-4-Fluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.