Description

1H-Spiro[Furo[3,4-C]Pyridine-3,4'-Piperidine] Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1224895-26-4. This compound is a critical building block in modern medicinal chemistry, valued for its complex spirocyclic and fused heterocyclic architecture which is essential for developing novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and synthesis of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other targeted therapies.

Application

This specialized intermediate serves as a key structural motif in several high-value research and development areas:

• Pharmaceutical Research & Development: A crucial precursor in the synthesis of novel drug candidates targeting neurological and psychiatric disorders.
• Active Pharmaceutical Ingredient (API) Synthesis: Used as a core scaffold in the multi-step manufacturing process of complex APIs.
• Medicinal Chemistry & Lead Optimization: Enables structure-activity relationship (SAR) studies to improve drug potency, selectivity, and pharmacokinetic properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery pipelines.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	1H-Spiro[Furo[3,4-C]Pyridine-3,4'-Piperidine] Hydrochloride
CAS No.	1224895-26-4
Molecular Formula	C11H14ClN2O
Molecular Weight	225.70 g/mol
Synonyms	1'H-Spiro[furo[3,4-c]pyridine-3,4'-piperidine] hydrochloride; Furo[3,4-c]pyridine-3(1H),4'-piperidine hydrochloride (1:1); 1H-Spiro(furo[3,4-c]pyridine-3,4'-piperidine) hydrochloride; 1224895-26-4; Spiro[furo[3,4-c]pyridine-3,4'-piperidine] hydrochloride; 1H-Spiro[furo[3,4-c]pyridine-3,4'-piperidine] HCl
EINECS	Contact for details

Quality Control

We supply 1H-Spiro[Furo[3,4-C]Pyridine-3,4'-Piperidine] Hydrochloride manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to exclude moisture and stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.