Description

4-Bromo-2-Fluoro-6-(Trifluoromethyl)Phenol is a high-value, multi-functional halogenated phenolic intermediate. This compound matters for its unique molecular architecture, which combines bromine, fluorine, and a trifluoromethyl group on a phenolic scaffold, offering versatile reactivity for advanced synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, contributing to the molecular design of liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce halogenated phenolic units into specialty polymers, improving flame retardancy and chemical resistance.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution reactions to introduce complex aromatic systems.

Basic Information

Product Name	4-Bromo-2-Fluoro-6-(Trifluoromethyl)Phenol
CAS No.	1224604-17-4
Molecular Formula	C7H3BrF4O
Molecular Weight	259.00 g/mol
Synonyms	2-Fluoro-4-bromo-6-(trifluoromethyl)phenol; 4-Bromo-2-fluoro-6-(trifluoromethyl)phenol; Phenol, 4-bromo-2-fluoro-6-(trifluoromethyl)-; 6-(Trifluoromethyl)-4-bromo-2-fluorophenol; 2-Fluoro-4-bromo-alpha,alpha,α-trifluoro-p-cresol
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2-Fluoro-6-(Trifluoromethyl)Phenol adheres to stringent internal quality standards, ensuring batch-to-batch consistency for critical R&D and scale-up work. Each lot is characterized by modern analytical techniques including HPLC, GC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.