Description

2-[4-(Pyrrolidin-1-Ylsulfonyl)Phenyl]Ethanamine Hydrochloride is a high-purity, specialized organic building block with a sulfonamide-linked pyrrolidine and phenethylamine core. This compound is valued for its role as a critical intermediate in the synthesis of novel bioactive molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Chemical Biology Probe Development: Used in medicinal chemistry to create tool compounds for studying enzyme inhibition or receptor modulation, leveraging the sulfonamide and amine functionalities.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, or plant growth regulators that incorporate sulfonamide pharmacophores.
• Material Science Applications: Potential monomer or additive for advanced polymers and functional materials requiring specific amine and sulfone groups.
• Academic & Contract Research: Essential for academic institutions and CROs (Contract Research Organizations) engaged in cutting-edge organic synthesis and heterocyclic chemistry projects.

Basic Information

Product Name	2-[4-(Pyrrolidin-1-Ylsulfonyl)Phenyl]Ethanamine Hydrochloride
CAS No.	1224170-51-7
Molecular Formula	C₁₂H₁₈N₂O₂S • HCl
Molecular Weight	290.81 g/mol (Free base: 254.35 g/mol)
Synonyms	4-(2-Aminoethyl)-N-(pyrrolidin-1-yl)benzenesulfonamide hydrochloride; 2-[4-(Pyrrolidine-1-sulfonyl)phenyl]ethan-1-amine hydrochloride; 1-[4-(2-Aminoethyl)phenyl]sulfonyl]pyrrolidine hydrochloride; N-(pyrrolidin-1-yl)-4-(2-aminoethyl)benzenesulfonamide HCl; 4-(2-Aminoethyl)benzenesulfonamide, N-pyrrolidinyl-, hydrochloride; 1224170-51-7; (4-(2-Aminoethyl)phenyl)(pyrrolidin-1-yl)sulfone hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-[4-(Pyrrolidin-1-Ylsulfonyl)Phenyl]Ethanamine Hydrochloride is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles via HPLC, NMR, and MS is supplied with each shipment. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.