Description

(E)-tert-Butyl 2-(4-(3-(Hydroxyamino)-3-Oxoprop-1-En-1-Yl)Benzoyl)Hydrazinecarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique hydroxamic acid and hydrazinecarboxylate functional groups. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting enzymatic pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of protease inhibitors and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those designed as enzyme inhibitors.
• Protease Inhibitor Research: Serves as a core scaffold for developing inhibitors targeting metalloproteases and other hydrolytic enzymes due to its hydroxamic acid moiety.
• Medicinal Chemistry & Lead Optimization: Used in structure-activity relationship (SAR) studies to explore and optimize the pharmacophore of new chemical entities.
• Bioconjugation & Chemical Biology: The reactive hydrazine and hydroxamate groups can be utilized for labeling or conjugating biomolecules in probe development.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce specific functional complexity into target molecules.

Basic Information

Product Name	(E)-tert-Butyl 2-(4-(3-(Hydroxyamino)-3-Oxoprop-1-En-1-Yl)Benzoyl)Hydrazinecarboxylate
CAS No.	1223593-73-4
Molecular Formula	C15H19N3O5
Molecular Weight	321.33 g/mol
Synonyms	tert-Butyl (2E)-2-[(4-[(1E)-3-(hydroxyamino)-3-oxoprop-1-en-1-yl]benzoyl)hydrazinecarboxylate; (E)-tert-Butyl (2E)-2-(4-((1E)-3-(Hydroxyamino)-3-oxoprop-1-en-1-yl)benzoyl)hydrazinecarboxylate; N'-tert-Butoxycarbonyl-4-[(1E)-3-(hydroxyamino)-3-oxoprop-1-en-1-yl]benzohydrazide; BOC-Hydroxamic Acid Hydrazide Derivative; 4-(3-Hydroxyamino-3-oxo-1-propenyl)benzoic Acid tert-Butyl Carbazate
EINECS	Contact for details

Quality Control

Our (E)-tert-Butyl 2-(4-(3-(Hydroxyamino)-3-Oxoprop-1-En-1-Yl)Benzoyl)Hydrazinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.