Description

(S)-1-Amino-8-(Diphenylphosphino)-1,2,3,4-Tetrahydronaphthalene is a chiral, P,N-bidentate ligand of significant interest in asymmetric catalysis. Its value lies in its ability to coordinate with transition metals to form highly selective catalysts for a variety of organic transformations. This compound is primarily needed by researchers and process chemists in the pharmaceutical and fine chemical industries for the development of enantioselective synthetic routes.

Application

• As a key chiral ligand in asymmetric hydrogenation reactions for the synthesis of enantiomerically pure pharmaceutical intermediates.
• Utilized in asymmetric C-C bond-forming reactions, such as cross-coupling and allylic substitution.
• Employed in the development of novel transition metal catalysts for academic and industrial research.
• Critical for the synthesis of optically active compounds in medicinal chemistry programs.
• Used in process chemistry to improve the selectivity and yield of chiral active pharmaceutical ingredients (APIs).
• Application in asymmetric hydroformylation and other catalytic carbonylation processes.

Basic Information

Product Name	(S)-1-Amino-8-(Diphenylphosphino)-1,2,3,4-Tetrahydronaphthalene
CAS No.	1222630-45-6
Molecular Formula	C22H22NP
Molecular Weight	331.39 g/mol
Synonyms	(S)-1-Amino-8-(diphenylphosphino)-1,2,3,4-tetrahydronaphthalene; (S)-1-Amino-8-diphenylphosphino-1,2,3,4-tetrahydronaphthalene; (S)-8-(Diphenylphosphino)-1,2,3,4-tetrahydro-1-naphthylamine; (S)-1-NH2-8-PPh2-Tetralin; (S)-1-Amino-8-(diphenylphosphanyl)-1,2,3,4-tetrahydronaphthalene; (S)-1,2,3,4-Tetrahydro-8-(diphenylphosphino)-1-naphthalenamine; (S)-P,N-Tetralin Ligand
EINECS	Contact for details

Quality Control

Our production of (S)-1-Amino-8-(Diphenylphosphino)-1,2,3,4-Tetrahydronaphthalene adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. All materials are characterized by advanced analytical techniques, including chiral HPLC and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C). This compound is easily oxidized and moisture-sensitive; therefore, containers should be opened only in a dry, inert environment and resealed immediately after use.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.