Description

2-((2-Bromo-4-Fluorobenzyl)Oxy)Tetrahydro-2H-Pyran is a high-purity, advanced pharmaceutical intermediate featuring a unique halogenated benzyl-protected alcohol structure. This compound is critical for enabling complex synthetic routes in medicinal chemistry, particularly for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build complex molecular architectures with precision.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its halogenated aromatic system for bioactivity.
• Organic Synthesis Reagent: Serves as a protected alcohol synthon in multi-step organic synthesis, facilitating reactions that are sensitive to free hydroxyl groups.
• Material Science Precursor: Employed in the research and development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes to study enzyme function and biological pathways.

Basic Information

Item	Details
Product Name	2-((2-Bromo-4-Fluorobenzyl)Oxy)Tetrahydro-2H-Pyran
CAS No.	1222010-84-5
Molecular Formula	C12H14BrFO2
Molecular Weight	289.14 g/mol
Synonyms	2-[(2-Bromo-4-fluorophenyl)methoxy]oxane; 2-((2-Bromo-4-fluorobenzyl)oxy)oxane; THP Ether of 2-Bromo-4-fluorobenzyl alcohol; 2-Bromo-4-fluorobenzyl tetrahydropyran-2-yl ether; 2-(2-Bromo-4-fluorobenzyloxy)tetrahydropyran; 2-Bromo-4-fluorobenzyl THP ether; 2-Bromo-4-fluoro-α-(tetrahydro-2H-pyran-2-yloxy)toluene
EINECS	Contact for details

Quality Control

Every batch of 2-((2-Bromo-4-Fluorobenzyl)Oxy)Tetrahydro-2H-Pyran is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom purity grades (e.g., >98%, >99%) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.