Description

5-Bromo-6-Cyclopropyl-1H-Pyrazolo[3,4-B]Pyridin-3-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrazolopyridine class of heterocyclic compounds. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel, small-molecule drug candidates targeting various therapeutic areas. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutics for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry & API Development: Used in route scouting, optimization, and scale-up processes for the manufacture of clinical trial materials and commercial APIs.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme function and cellular signaling pathways.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents.

Basic Information

Product Name	5-Bromo-6-Cyclopropyl-1H-Pyrazolo[3,4-B]Pyridin-3-Amine
CAS No.	1221792-47-7
Molecular Formula	C9H9BrN4
Molecular Weight	253.10 g/mol
Synonyms	5-Bromo-6-cyclopropyl-1H-pyrazolo[3,4-b]pyridin-3-amine; 5-Bromo-6-cyclopropyl-3-amino-1H-pyrazolo[3,4-b]pyridine; 1221792-47-7; 6-Cyclopropyl-5-bromo-1H-pyrazolo[3,4-b]pyridin-3-amine; 3-Amino-5-bromo-6-cyclopropyl-1H-pyrazolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Cyclopropyl-1H-Pyrazolo[3,4-B]Pyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.