Description

1-(3-Bromophenyl)-5-(Trifluoromethyl)-1H-1,2,3-Triazole-4-Carboxylic Acid is a high-value, multifunctional heterocyclic building block designed for advanced chemical synthesis. Its core value lies in the strategic combination of a bromophenyl group, a trifluoromethyl group, and a carboxylic acid functionality on a 1,2,3-triazole scaffold, enabling precise molecular modifications and the introduction of key physicochemical properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate for creating novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for incorporating the trifluoromethyl group to enhance metabolic stability and membrane permeability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique halogenated and fluorinated structure for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent for creating specialized polymers, coatings, or liquid crystals with tailored properties.
• Chemical Biology Probe: Utilized in click chemistry and bioconjugation strategies to label biomolecules or construct complex molecular architectures for diagnostic and research purposes.
• Organic Synthesis Reagent: Acts as a versatile synthon for constructing more complex heterocyclic systems or for further functionalization via its carboxylic acid and bromoaryl groups.

Basic Information

Product Name	1-(3-Bromophenyl)-5-(Trifluoromethyl)-1H-1,2,3-Triazole-4-Carboxylic Acid
CAS No.	1221725-66-1
Molecular Formula	C10H5BrF3N3O2
Molecular Weight	336.07 g/mol
Synonyms	5-(Trifluoromethyl)-1-(3-bromophenyl)-1H-1,2,3-triazole-4-carboxylic acid; 1-(3-Bromophenyl)-5-(trifluoromethyl)-1,2,3-triazole-4-carboxylic acid; 1H-1,2,3-Triazole-4-carboxylic acid, 1-(3-bromophenyl)-5-(trifluoromethyl)-; 3-Bromo-5-(trifluoromethyl)-1,2,3-triazole-4-carboxylic acid phenyl derivative; (3-Bromophenyl)-5-trifluoromethyl-1H-[1,2,3]triazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(3-Bromophenyl)-5-(Trifluoromethyl)-1H-1,2,3-Triazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment and are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed when not in use to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.