Description

8-Bromo-1,2,3,4-Tetrahydroquinoline Hydrochloride is a high-purity, halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in providing a functionalized tetrahydroquinoline scaffold, which is a privileged structure in medicinal chemistry for drug discovery and development. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, serving as a key intermediate for the synthesis of novel bioactive molecules and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to the bioactive nature of the tetrahydroquinoline core.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in the study of biological pathways and protein interactions.
• Material Science: Serves as a precursor for the synthesis of advanced organic materials, including ligands for catalysis and functional polymers.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic routes in academic and industrial R&D laboratories.

Basic Information

Product Name	8-Bromo-1,2,3,4-Tetrahydroquinoline Hydrochloride
CAS No.	1221724-17-9
Molecular Formula	C9H10BrN·HCl
Molecular Weight	248.55 g/mol
Synonyms	8-Bromo-1,2,3,4-tetrahydroquinoline HCl; 8-Bromo-1,2,3,4-tetrahydroquinoline hydrochloride; 1,2,3,4-Tetrahydro-8-bromoquinoline hydrochloride; Quinoline, 8-bromo-1,2,3,4-tetrahydro-, hydrochloride; 8-Bromo-1,2,3,4-tetrahydroquinoline monohydrochloride
EINECS	Contact for details

Quality Control

Our 8-Bromo-1,2,3,4-Tetrahydroquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications in GMP and ISO-compliant research and production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.