Description

1-(Azetidin-3-Yl)-1H-Pyrazole Hydrochloride is a high-purity, heterocyclic building block essential for modern pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the fields of oncology and central nervous system (CNS) therapeutics. It is primarily utilized by medicinal chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecular scaffolds in drug discovery programs.
• Medicinal Chemistry Research: Used in the design and synthesis of new chemical entities (NCEs) targeting various biological pathways.
• API Synthesis: Serves as a building block in the multi-step synthesis of potential therapeutic agents.
• Chemical Biology: Employed in the development of chemical probes and tool compounds for target validation.
• Process Research & Development (R&D): Used to develop and optimize scalable synthetic routes for candidate drugs.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	1-(Azetidin-3-Yl)-1H-Pyrazole Hydrochloride
CAS No.	1221715-95-2
Molecular Formula	C6H10ClN3
Molecular Weight	159.62 g/mol
Synonyms	1-(Azetidin-3-yl)-1H-pyrazole hydrochloride; 1H-Pyrazole, 1-(3-azetidinyl)-, hydrochloride; 3-(1H-Pyrazol-1-yl)azetidine hydrochloride; Azetidine, 3-(1H-pyrazol-1-yl)-, hydrochloride; 1-(Azetidin-3-yl)-1H-pyrazole HCl; 1221715-95-2
EINECS	Contact for details

Quality Control

Our 1-(Azetidin-3-Yl)-1H-Pyrazole Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.