Description

6-Amino-5-Bromopicolinic Acid is a high-value brominated picolinic acid derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in its bifunctional structure, featuring both an amino group and a bromine atom on the pyridine ring, which enables precise and versatile derivatization for creating complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, metal-organic frameworks (MOFs), and organic electronic materials.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Item	Detail
Product Name	6-Amino-5-Bromopicolinic Acid
CAS No.	1221629-04-4
Molecular Formula	C6H5BrN2O2
Molecular Weight	217.02 g/mol
Synonyms	5-Bromo-6-aminopicolinic acid; 2-Amino-5-bromo-6-pyridinecarboxylic acid; 5-Bromo-6-amino-2-pyridinecarboxylic acid; 6-Amino-5-bromopyridine-2-carboxylic acid; 2-Carboxy-5-bromo-6-aminopyridine; Picolinic acid, 6-amino-5-bromo-; (6-Amino-5-bromopyridin-2-yl)methanol (oxidized form); Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Every batch of 6-Amino-5-Bromopicolinic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC purity, identity confirmation via spectroscopic methods (IR, NMR, MS), and quantification of key impurities. Our quality commitment ensures material suitability for research and development through to pilot-scale cGMP synthesis, supporting regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.