Description

tert-Butyl 5-Oxo-4,9-Diazaspiro[5.5]Undecan-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic diaza scaffold. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry and process R&D for innovative drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug molecules, especially those targeting the central nervous system (CNS) and oncology.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in hit-to-lead and lead optimization campaigns, enabling exploration of new chemical space.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the production of candidate drugs under Good Manufacturing Practice (GMP) guidelines.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity chemical building blocks.
• Academic Research: Utilized in university and institutional labs for studying novel heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	tert-Butyl 5-Oxo-4,9-Diazaspiro[5.5]Undecan-4-Carboxylate
CAS No.	1221449-51-9
Molecular Formula	C14H24N2O3
Molecular Weight	268.35 g/mol
Synonyms	4-(tert-Butoxycarbonyl)-4,9-diazaspiro[5.5]undecan-5-one; 4,9-Diazaspiro[5.5]undecan-5-one, 4-[(1,1-dimethylethoxy)carbonyl]-; tert-Butyl 5-oxo-4,9-diazaspiro[5.5]undecane-4-carboxylate; 4-Boc-4,9-diazaspiro[5.5]undecan-5-one; 4-N-Boc-4,9-diazaspiro[5.5]undecan-5-one; 4,9-Diazaspiro[5.5]undecane-5-one, 4-(tert-butoxycarbonyl)-; 1221449-51-9; Boc-protected diazaspiro undecanone
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Oxo-4,9-Diazaspiro[5.5]Undecan-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP standards where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.