Description

2,2,2-Trifluoro-1-(4-Trifluoromethylphenyl)Ethylamine Hydrochloride is a high-value fluorinated aromatic amine hydrochloride salt, a key building block in advanced organic synthesis. Its unique structure, featuring two trifluoromethyl groups, provides exceptional metabolic stability and lipophilicity, making it a critical intermediate for developing novel active compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to incorporate fluorine motifs for enhanced bioactivity and patent life.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing CNS agents, anti-inflammatory drugs, and kinase inhibitors.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides where the trifluoromethyl groups enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent for specialty polymers, liquid crystals, and advanced organic electronic materials.
• Fluorine Chemistry & Labeling: Employed in 18F or 19F-based radiochemistry for PET imaging tracers and as a stable isotope label in metabolic studies.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2,2,2-Trifluoro-1-(4-Trifluoromethylphenyl)Ethylamine Hydrochloride
CAS No.	1220039-72-4
Molecular Formula	C9H7ClF6N
Molecular Weight	278.60 g/mol
Synonyms	α,α,α-Trifluoro-4-(trifluoromethyl)benzeneethanamine Hydrochloride; 1-[4-(Trifluoromethyl)phenyl]-2,2,2-trifluoroethylamine Hydrochloride; 2,2,2-Trifluoro-1-[4-(trifluoromethyl)phenyl]ethan-1-amine Hydrochloride; 4-(Trifluoromethyl)benzylamine, α,α,α-trifluoro-, Hydrochloride; (4-Trifluoromethylphenyl)trifluoroethylamine HCl; 2,2,2-Trifluoro-1-(4-trifluoromethylphenyl)ethanamine Hydrochloride
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(4-Trifluoromethylphenyl)Ethylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.