Description

1-Bromo-3-Cyclopropylmethanesulfonyl-Benzene is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonyl and bromo-substituted aromatic structure. This compound is critical for medicinal chemists as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules. It is primarily utilized in research and development for drug discovery programs targeting a range of therapeutic areas, including oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Organic Synthesis Reagent: Serves as a versatile electrophile or coupling partner in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Agrochemical Development: Employed in the research and synthesis of novel crop protection agents and pesticides.
• Material Science: Potential precursor for the development of specialty polymers and advanced organic electronic materials.

Basic Information

Product Name	1-Bromo-3-Cyclopropylmethanesulfonyl-Benzene
CAS No.	1220039-45-1
Molecular Formula	C10H11BrO2S
Molecular Weight	275.16 g/mol
Synonyms	3-Bromophenyl cyclopropylmethyl sulfone; 1-Bromo-3-(cyclopropylmethylsulfonyl)benzene; Benzene, 1-bromo-3-[(cyclopropylmethyl)sulfonyl]-; Cyclopropylmethyl 3-bromophenyl sulfone; (3-Bromophenyl)(cyclopropylmethyl) sulfone
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Cyclopropylmethanesulfonyl-Benzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.