Description

2-(3-Piperidinyl)-1,2,3,4-Tetrahydroisoquinolinedihydrochloride is a high-purity, non-racemic organic salt with significant potential in advanced pharmaceutical research and development. This compound serves as a critical chiral building block and pharmacological intermediate for the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and neuroscience.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential neuroactive compounds and receptor modulators.
• Medicinal Chemistry Research: Building block for creating focused libraries to explore structure-activity relationships (SAR) in drug discovery programs.
• Neuroscience R&D: Investigational tool for studying ligand-receptor interactions related to neurological pathways.
• Process Chemistry Development: Used in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in related synthetic processes.

Basic Information

Product Name	2-(3-Piperidinyl)-1,2,3,4-Tetrahydroisoquinolinedihydrochloride
CAS No.	1220037-92-2
Molecular Formula	C14H20N2·2HCl
Molecular Weight	289.24 g/mol (free base: 216.32 g/mol)
Synonyms	1,2,3,4-Tetrahydro-2-(3-piperidinyl)isoquinoline dihydrochloride; 2-(Piperidin-3-yl)-1,2,3,4-tetrahydroisoquinoline dihydrochloride; (R/S)-2-(3-Piperidyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride; 2-(3-Piperidyl)-1,2,3,4-tetrahydroisoquinoline dihydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Piperidinyl)-1,2,3,4-Tetrahydroisoquinolinedihydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure compliance with exacting R&D standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and research documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.