Description

3-{[4-(Trifluoromethyl)Phenoxy]Methyl}Piperidinehydrochloride is a high-purity, advanced pharmaceutical intermediate and organic building block. This compound is valued for its unique molecular structure, which incorporates a trifluoromethylphenoxy moiety, making it a critical synthon for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging the biological activity of the piperidine and trifluoromethylphenyl groups.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and receptor interactions.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with specific thermal or surface properties.

Basic Information

Product Name	3-{[4-(Trifluoromethyl)Phenoxy]Methyl}Piperidinehydrochloride
CAS No.	1220037-57-9
Molecular Formula	C14H17ClF3NO
Molecular Weight	307.74 g/mol
Synonyms	3-((4-(Trifluoromethyl)phenoxy)methyl)piperidine hydrochloride; 1-(4-(Trifluoromethyl)phenoxymethyl)-3-piperidine hydrochloride; Piperidine, 3-[[[4-(trifluoromethyl)phenyl]oxy]methyl]-, hydrochloride (1:1); 3-((4-(Trifluoromethyl)phenoxy)methyl)piperidine HCl; 1220037-57-9
EINECS	Contact for details

Quality Control

Our 3-{[4-(Trifluoromethyl)Phenoxy]Methyl}Piperidinehydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.