Description

1-(Pyrrolidin-2-Ylmethyl)Piperidine 2Hcl is a high-purity, versatile organic building block and intermediate of significant interest in advanced chemical synthesis. Its value lies in its unique bicyclic amine structure, which is crucial for constructing complex molecules in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key scaffold in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, receptor modulators, and enzyme inhibitors.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, leveraging its heterocyclic amine functionality.
• Ligand and Catalyst Precursor: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis and metal complexation.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Institutional Research: Used in universities and research institutes for methodological development and exploring new chemical spaces.

Basic Information

Product Name	1-(Pyrrolidin-2-Ylmethyl)Piperidine 2Hcl
CAS No.	1220027-38-2
Molecular Formula	C10H22Cl2N2
Molecular Weight	241.20 g/mol
Synonyms	1-[(Pyrrolidin-2-yl)methyl]piperidine dihydrochloride; Piperidine, 1-[(2-pyrrolidinyl)methyl]-, dihydrochloride; 1-(Pyrrolidin-2-ylmethyl)piperidine dihydrochloride; 1-(2-Pyrrolidinylmethyl)piperidine 2HCl; 1-(Pyrrolidin-2-Ylmethyl)Piperidine Dihydrochloride; 1220027-38-2
EINECS	Contact for details

Quality Control

Our 1-(Pyrrolidin-2-Ylmethyl)Piperidine 2Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with complete batch data are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.