Description

1-(3-Piperidinylmethyl)-1,2,3,4-Tetrahydroquinoline Dihydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific heterocyclic structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for synthesizing novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, particularly within the central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Reference Standard: Serves as a high-purity analytical standard for method development, quality control, and regulatory submissions.
• Biochemical Research: Employed in vitro studies to investigate biological activity and mechanism of action for novel compounds.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.

Basic Information

Product Name	1-(3-Piperidinylmethyl)-1,2,3,4-Tetrahydroquinoline Dihydrochloride
CAS No.	1220021-34-0
Molecular Formula	C15H22N2·2HCl
Molecular Weight	295.27 g/mol (Free base: 230.35 g/mol)
Synonyms	1-[(Piperidin-3-yl)methyl]-1,2,3,4-tetrahydroquinoline dihydrochloride; 1,2,3,4-Tetrahydro-1-[(3-piperidinyl)methyl]quinoline dihydrochloride; Quinoline, 1,2,3,4-tetrahydro-1-[(3-piperidinyl)methyl]-, dihydrochloride; 1-(Piperidin-3-ylmethyl)-3,4-dihydro-1H-quinoline dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(3-Piperidinylmethyl)-1,2,3,4-Tetrahydroquinoline Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.