Description

4-{[4-(Trifluoromethyl)Phenoxy]Methyl}Piperidinehydrochloride is a high-value, functionalized piperidine derivative and a key synthetic intermediate in modern organic chemistry. Its core value proposition lies in the unique combination of the piperidine scaffold and the trifluoromethylphenoxy moiety, which is critical for modulating the physicochemical and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who are developing new active ingredients, particularly for applications requiring specific receptor binding or metabolic stability.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances bioactivity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and liquid crystals with tailored thermal and optical properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and protein-protein interactions in biological systems.

Basic Information

Product Name	4-{[4-(Trifluoromethyl)Phenoxy]Methyl}Piperidinehydrochloride
CAS No.	1219982-20-3
Molecular Formula	C14H17ClF3NO
Molecular Weight	307.74 g/mol
Synonyms	4-[(4-Trifluoromethylphenoxy)methyl]piperidine hydrochloride; 1-[(4-Trifluoromethylphenoxy)methyl]piperidin-4-yl hydrochloride; 4-(4-Trifluoromethylphenoxymethyl)piperidine HCl; Piperidine, 4-[[[4-(trifluoromethyl)phenyl]oxy]methyl]-, hydrochloride (1:1); 4-({[4-(Trifluoromethyl)phenyl]oxy}methyl)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-{[4-(Trifluoromethyl)Phenoxy]Methyl}Piperidinehydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.