Description

2-{2-[2-(Trifluoromethyl)Phenoxy]Ethyl}Piperidinehydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct trifluoromethylphenoxy structural motif. This compound is critical for medicinal chemistry research and development, offering a versatile building block for synthesizing novel bioactive molecules. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of new therapeutic agents, particularly in the areas of central nervous system (CNS) and metabolic disorder treatments.

Application

• Key synthetic intermediate in the research and development of new active pharmaceutical ingredients (APIs).
• Building block for medicinal chemistry, enabling structure-activity relationship (SAR) studies in drug discovery programs.
• Precursor in the synthesis of potential therapeutic compounds targeting neurological and psychiatric disorders.
• Used in the development of ligands for various biological receptors and enzymes in preclinical research.
• Valuable material for process chemistry development and scale-up studies in fine chemical production.
• Reference standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	2-{2-[2-(Trifluoromethyl)Phenoxy]Ethyl}Piperidinehydrochloride
CAS No.	1219982-12-3
Molecular Formula	C14H18F3NO•HCl
Molecular Weight	309.76 g/mol (free base)
Synonyms	2-[2-[2-(Trifluoromethyl)phenoxy]ethyl]piperidine hydrochloride; 1-[2-[2-(Trifluoromethyl)phenoxy]ethyl]piperidine hydrochloride; α,2,2-Trifluoro-m-phenoxyethylpiperidine HCl; 2-(2-(2-(Trifluoromethyl)phenoxy)ethyl)piperidine HCl; 2-(2-(o-Trifluoromethylphenoxy)ethyl)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-{2-[2-(Trifluoromethyl)Phenoxy]Ethyl}Piperidinehydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), residual solvents, and other critical parameters is provided with each shipment to guarantee reliable and reproducible performance in your synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.