Description

3-{2-[(5-Bromo[1,1'-Biphenyl]-2-Yl)Oxy]-Ethyl}Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex biphenyl-piperidine hybrid structure. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the creation of new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Ligand Synthesis: Employed in the development of novel ligands for receptors and enzymes within drug discovery programs.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and pharmacology.

Basic Information

Product Name	3-{2-[(5-Bromo[1,1'-Biphenyl]-2-Yl)Oxy]-Ethyl}Piperidine Hydrochloride
CAS No.	1219967-24-4
Molecular Formula	C19H22BrNO•HCl
Molecular Weight	396.75 g/mol (Free base: 360.29 g/mol)
Synonyms	3-[2-[(5-Bromo[1,1'-biphenyl]-2-yl)oxy]ethyl]piperidine hydrochloride; 5-Bromo-2'-(2-(piperidin-3-yl)ethoxy)-1,1'-biphenyl hydrochloride; 3-(2-((5-Bromobiphenyl-2-yl)oxy)ethyl)piperidine HCl; Biphenyl-piperidine derivative hydrochloride salt; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3-{2-[(5-Bromo[1,1'-Biphenyl]-2-Yl)Oxy]-Ethyl}Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.