Description

6-Chloro-4-Hydroxy-[1,8]Naphthyridine is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting infectious diseases or cancer.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides due to its bioactive naphthyridine core.
• Ligand Synthesis: Serves as a starting material for creating chelating ligands in coordination chemistry and catalysis.
• Material Science: Can be incorporated into the design of organic electronic materials or fluorescent probes.
• Academic & Contract Research: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	6-Chloro-4-Hydroxy-[1,8]Naphthyridine
CAS No.	1219815-54-9
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	4-Hydroxy-6-chloro[1,8]naphthyridine; 6-Chloro-4-hydroxy-1,8-naphthyridine; 6-Chloro-1,8-naphthyridin-4-ol; 6-Chloro-4(1H)-[1,8]naphthyridinone; 4-Hydroxy-6-chloro-1,8-naphthyridine
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-Hydroxy-[1,8]Naphthyridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.