Description

2,2',5,5'-Tetrachlorobiphenyl-3,4,6-D3 is a deuterated isotopologue of a specific tetrachlorinated biphenyl congener, serving as a critical analytical standard for precise environmental and toxicological research. This compound matters for its role in enabling accurate quantification and tracing of polychlorinated biphenyl (PCB) metabolites and congeners via advanced mass spectrometry techniques. It is primarily needed by analytical laboratories, environmental testing facilities, and research institutions focused on persistent organic pollutant (POP) analysis, method development, and regulatory compliance.

Application

• Internal Standard for Mass Spectrometry: Used as a deuterium-labeled internal standard in GC-MS and LC-MS/MS analysis for the accurate quantification of PCBs and their metabolites in complex matrices.
• Environmental Monitoring: Essential for tracing and quantifying specific PCB congeners in soil, water, sediment, and air samples to assess contamination levels and environmental fate.
• Metabolite Studies: Facilitates research into the biotransformation, pharmacokinetics, and toxicokinetics of PCBs in biological systems.
• Method Development & Validation: Serves as a reference material for developing, calibrating, and validating analytical methods in accordance with EPA, EU, and other international standards.
• Food & Feed Safety Analysis: Employed in the analysis of PCB residues to ensure compliance with safety regulations in the food supply chain.
• Forensic and Source Identification: Aids in chemical fingerprinting to identify the sources and history of PCB contamination.

Basic Information

Product Name	2,2',5,5'-Tetrachlorobiphenyl-3,4,6-D3
CAS No.	1219794-74-7
Molecular Formula	C12H3D3Cl4
Molecular Weight	295.98 g/mol (for D3 isotopologue)
Synonyms	PCB 52-D3; 2,2',5,5'-Tetrachloro[3,4,6-D3]biphenyl; 2,2',5,5'-Tetrachlorobiphenyl-d3; Deuterated PCB 52; 2,2',5,5'-Tetrachloro-1,1'-biphenyl-3,4,6-D3; Tetrachlorobiphenyl D3 Standard; [D3]-2,2',5,5'-Tetrachlorobiphenyl
EINECS	Contact for details

Quality Control

Every batch of 2,2',5,5'-Tetrachlorobiphenyl-3,4,6-D3 is produced and analyzed under strict quality protocols to ensure the highest isotopic and chemical purity for trace analysis. Our quality assurance includes verification of isotopic enrichment (D3), chemical purity, and congener specificity using advanced spectroscopic and chromatographic techniques. A comprehensive Certificate of Analysis (COA) detailing batch-specific results, including assay by GC-MS or HPLC, isotopic purity, and solvent content, is provided with each shipment to support your quality and compliance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC / GC)	≥ 98% (Chemical Purity)
Isotopic Purity (D3)	≥ 98 atom % D
Isotopic Enrichment (MS)	≥ 99% (D3)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.