Description

2-[(2-Methylpropyl)Amino]-n-[4-(1H-1,2,4-Triazol-1-Ylmethyl)Phenyl]-1,3-Thiazole-4-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular architecture combining thiazole and triazole heterocycles. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted biological activity. It is primarily needed by pharmaceutical R&D organizations and fine chemical manufacturers engaged in developing next-generation treatments.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Antifungal Agent Research: Used in the research and development of new triazole-based antifungal compounds due to its structural motif.
• Kinase Inhibitor Development: Acts as a core scaffold in medicinal chemistry programs focused on creating protein kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Research: Employed in the discovery of new crop protection agents, leveraging its heterocyclic system for bioactivity.
• Chemical Biology Probes: Utilized as a specialized building block for creating molecular probes to study biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	2-[(2-Methylpropyl)Amino]-n-[4-(1H-1,2,4-Triazol-1-Ylmethyl)Phenyl]-1,3-Thiazole-4-Carboxamide
CAS No.	1219573-87-1
Molecular Formula	C17H20N6OS
Molecular Weight	356.45 g/mol
Synonyms	N-(4-((1H-1,2,4-Triazol-1-yl)methyl)phenyl)-2-((2-methylpropyl)amino)thiazole-4-carboxamide; 2-(Isobutylamino)-N-[4-(1H-1,2,4-triazol-1-ylmethyl)phenyl]-1,3-thiazole-4-carboxamide; Thiazole-4-carboxamide, 2-[(2-methylpropyl)amino]-N-[4-[(1H-1,2,4-triazol-1-yl)methyl]phenyl]-; UNII-9S2F5P4C4T; 9S2F5P4C4T; 2-(2-Methylpropylamino)-N-(4-(1,2,4-triazol-1-ylmethyl)phenyl)thiazole-4-carboxamide
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to ensure structural identity and purity. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical quality attributes. For projects requiring specific regulatory support, we can discuss compliance with ICH guidelines and other relevant standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.