Description

1-[3-(4-Bromo-1H-Indol-1-Yl)Propanoyl]Piperidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for research and development in medicinal chemistry. This compound is valued for its role as a key building block in the synthesis of novel bioactive molecules, particularly those targeting neurological and oncological pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those containing indole and piperidine pharmacophores.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new active pharmaceutical ingredients (APIs).
• Protease Inhibitor Development: Serves as a core scaffold for the design and synthesis of potential protease enzyme inhibitors.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client-specific research programs.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	1-[3-(4-Bromo-1H-Indol-1-Yl)Propanoyl]Piperidine-4-Carboxylic Acid
CAS No.	1219547-57-5
Molecular Formula	C17H19BrN2O3
Molecular Weight	379.25 g/mol
Synonyms	4-Bromo-1-[3-(4-piperidinecarbonyl)propyl]indole; 4-Bromo-1-[3-(4-carboxypiperidino)propionyl]indole; 1-[3-(4-Bromo-1H-indol-1-yl)propanoyl]piperidine-4-carboxylic acid; 4-Bromo-1H-indole-1-propanoyl piperidine-4-carboxylic acid; Piperidine-4-carboxylic acid, 1-[3-(4-bromo-1H-indol-1-yl)-1-oxopropyl]-; 1219547-57-5; 4-Bromo-1-(3-oxo-3-(piperidin-4-yl)propyl)-1H-indole-4-carboxylic acid (tautomeric form)
EINECS	Contact for details

Quality Control

Our 1-[3-(4-Bromo-1H-Indol-1-Yl)Propanoyl]Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.