Description

Difluoromethyl 2-Pyridyl Sulfone is a specialized organosulfur compound featuring a reactive difluoromethyl group attached to a pyridyl sulfone scaffold. This unique structure makes it a valuable and versatile building block in modern synthetic organic chemistry, particularly for the introduction of the difluoromethyl moiety. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) containing the difluoromethyl group, which can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the difluoromethyl group is a critical functional element.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and specialty materials with tailored properties.
• Cross-Coupling Reactions: Acts as an electrophilic reagent in transition-metal catalyzed cross-coupling reactions to construct complex molecular architectures.
• Fluorine Chemistry: An essential reagent for medicinal and synthetic chemists exploring structure-activity relationships (SAR) by incorporating fluorine atoms into target molecules.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the efficient, large-scale production of fluorinated compounds.

Basic Information

Product Name	Difluoromethyl 2-Pyridyl Sulfone
CAS No.	1219454-89-3
Molecular Formula	C6H5F2NO2S
Molecular Weight	193.17 g/mol
Synonyms	2-((Difluoromethyl)sulfonyl)pyridine; Pyridine, 2-[(difluoromethyl)sulfonyl]-; (Pyridin-2-yl)difluoromethyl sulfone; Difluoromethyl Pyridin-2-yl Sulfone; 2-Pyridyl Difluoromethyl Sulfone
EINECS	Contact for details

Quality Control

Our Difluoromethyl 2-Pyridyl Sulfone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.