Description

Amino-(2-Bromo-Phenyl)-Acetic Acid Methyl Ester Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic structure. This compound is critical for enabling the synthesis of complex, biologically active molecules, offering researchers and manufacturers a reliable building block for drug discovery and development. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical and agrochemical sectors seeking to introduce specific bromo-phenyl and amino-acid ester functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the bromo-phenyl moiety can contribute to specific biological activity.
• Peptidomimetics & Bio-conjugates: Serves as a precursor for constructing non-natural amino acid derivatives used in peptide-mimetic drug design and linker chemistry for antibody-drug conjugates (ADCs).
• Chemical Biology Probes: Employed in the creation of specialized molecular probes and inhibitors for studying enzyme mechanisms and protein function.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic materials requiring functionalized aromatic units.

Basic Information

Product Name	Amino-(2-Bromo-Phenyl)-Acetic Acid Methyl Ester Hydrochloride
CAS No.	1219408-44-2
Molecular Formula	C9H11BrClNO2
Molecular Weight	280.55 g/mol
Synonyms	Methyl 2-amino-2-(2-bromophenyl)acetate hydrochloride; 2-Amino-2-(2-bromophenyl)acetic acid methyl ester hydrochloride; (2-Bromophenyl)glycine methyl ester hydrochloride; Methyl (2-bromophenyl)glycinate hydrochloride; Amino(2-bromophenyl)acetic acid methyl ester HCl; 2-Bromo-α-(methoxycarbonyl)benzylamine hydrochloride
EINECS	Contact for details

Quality Control

Our Amino-(2-Bromo-Phenyl)-Acetic Acid Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.