Description

Fmoc-2,4-Dinitro-Dl-Phenylglycine CAS NO 1219389-84-0 is a specialized, protected amino acid derivative designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise, racemic building blocks for constructing complex peptide sequences, particularly in solid-phase peptide synthesis (SPPS). It is primarily utilized in pharmaceutical research, process development, and the production of novel therapeutic peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key racemic building block for the controlled introduction of a 2,4-dinitrophenylglycine moiety into peptide chains.
• Pharmaceutical Research & Development: Used in the discovery and development of new peptide-based drugs, including enzyme inhibitors and receptor ligands.
• Combinatorial Chemistry Libraries: Serves as a versatile component for generating diverse peptide libraries for high-throughput screening.
• Process Development & Scale-Up: Employed in optimizing synthetic routes for the commercial production of peptide active pharmaceutical ingredients (APIs).
• Academic Research: A valuable reagent for studying peptide structure-activity relationships (SAR) and developing novel synthetic methodologies.
• Synthesis of Modified Peptides: Facilitates the creation of peptides with specific modifications to enhance stability, bioavailability, or biological activity.

Basic Information

Item	Details
Product Name	Fmoc-2,4-Dinitro-Dl-Phenylglycine
CAS No.	1219389-84-0
Molecular Formula	C23H17N3O8
Molecular Weight	463.40 g/mol
Synonyms	Fmoc-Dnp-DL-Phe-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2,4-dinitro-DL-phenylglycine; Fmoc-2,4-dinitrophenylglycine; Fmoc-DL-2,4-Dnp-OH; (RS)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-2-(2,4-dinitrophenyl)acetic acid; DL-Fmoc-2,4-Dinitrophenylglycine; N-Fmoc-2,4-dinitro-DL-phenylglycine; Fmoc-Dnp-DL-Phenylglycine
EINECS	Contact for details

Quality Control

Our Fmoc-2,4-Dinitro-Dl-Phenylglycine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.