Description

4-Bromo-5,6,7,8-tetrahydro-[1,5]naphthyridine-2-carboxylic acid is a high-value, heterocyclic building block of significant interest in modern organic synthesis and pharmaceutical research. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and other biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex organic targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition and other therapeutic pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transformations to construct complex polycyclic systems.
• Agrochemical Research: May serve as an intermediate in the development of new crop protection agents and herbicides.
• Material Science: Potential use in the synthesis of organic ligands for catalysts or functional materials.

Basic Information

Product Name	4-Bromo-5,6,7,8-tetrahydro-[1,5]naphthyridine-2-carboxylic acid
CAS No.	1219022-87-3
Molecular Formula	C9H9BrN2O2
Molecular Weight	257.09 g/mol
Synonyms	4-Bromo-5,6,7,8-tetrahydro-1,5-naphthyridine-2-carboxylic acid; 4-Bromo-5,6,7,8-tetrahydro[1,5]naphthyridine-2-carboxylic Acid; 2-Carboxy-4-bromo-5,6,7,8-tetrahydro-1,5-naphthyridine; 4-Bromo-5,6,7,8-tetrahydro-2-naphthyridinecarboxylic acid; 1219022-87-3; 4-Bromo-5,6,7,8-tetrahydro-1,5-naphthyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our 4-Bromo-5,6,7,8-tetrahydro-[1,5]naphthyridine-2-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.