Description

4-Amino-7-Chloro-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it provides a reliable and structurally defined building block for medicinal chemistry research and development, enabling the creation of novel therapeutic agents. It is primarily needed by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions focused on developing new drug candidates, particularly in the fields of anti-infectives and oncology.

Application

• Key intermediate in the synthesis of novel quinoline-based pharmaceutical compounds.
• Building block for research into potential antibacterial and antiviral agents.
• Precursor in the development of targeted cancer therapies and kinase inhibitors.
• Used in medicinal chemistry for structure-activity relationship (SAR) studies.
• Critical raw material for contract manufacturing organizations (CMOs) producing specialized APIs.
• Reference standard in analytical method development and quality control laboratories.

Basic Information

Product Name	4-Amino-7-Chloro-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1219022-82-8
Molecular Formula	C₁₄H₁₄ClN₂O₂
Molecular Weight	277.73 g/mol
Synonyms	Ethyl 4-Amino-7-Chloro-8-Methylquinoline-3-Carboxylate; 4-Amino-7-chloro-8-methylquinoline-3-carboxylic acid ethyl ester; 7-Chloro-8-methyl-4-aminoquinoline-3-carboxylic acid ethyl ester; 1219022-82-8; 4-Amino-7-chloro-8-methyl-3-quinolinecarboxylic acid ethyl ester; Ethyl 4-amino-7-chloro-8-methyl-3-quinolinecarboxylate; 3-Quinolinecarboxylic acid, 4-amino-7-chloro-8-methyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Amino-7-Chloro-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.