Description

2-Bromo-1,5-Naphthyridin-3-Amine is a high-purity, functionalized naphthyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated heterocyclic structure, which enables precise molecular modifications and the construction of complex pharmacophores. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and material science industries for applications in drug discovery, catalyst development, and the creation of novel functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators due to its bioactive heterocyclic core.
• Material Science: Serves as a monomer or functional additive in the creation of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Biology: Employed as a molecular probe or a tagging reagent in proteomics and bio-conjugation studies.
• Catalyst Ligand Synthesis: Utilized to construct sophisticated nitrogen-containing ligands for transition metal catalysis.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	2-Bromo-1,5-Naphthyridin-3-Amine
CAS No.	1219022-68-0
Molecular Formula	C8H6BrN3
Molecular Weight	224.06 g/mol
Synonyms	3-Amino-2-bromo-1,5-naphthyridine; 2-Bromo-1,5-naphthyridin-3-amine; 1,5-Naphthyridine, 2-bromo-3-amino-; 2-Bromo-3-amino-1,5-naphthyridine; 1219022-68-0; 2-Br-1,5-Nap-3-NH2; Bromoaminonaphthyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-1,5-Naphthyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.