Description

2-Amino-2-(3-Bromo-4-Methoxyphenyl)Acetic Acid is a specialized non-proteinogenic amino acid derivative featuring a brominated and methoxylated phenyl ring, making it a valuable chiral building block for advanced synthesis. This compound is essential for research and development in pharmaceutical chemistry, where it serves as a key intermediate in the creation of novel active pharmaceutical ingredients (APIs) and complex organic molecules. Its unique structure is particularly sought after by medicinal chemists and process development scientists working in drug discovery, agrochemical research, and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of potential drug candidates, especially in areas targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that require specific stereochemistry.
• Peptidomimetics & Bioactive Molecule Design: Serves as a constrained amino acid analog for constructing peptide-like molecules with enhanced stability and biological activity.
• Ligand & Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for incorporating a bromine "handle" into molecules for further functionalization via cross-coupling reactions or as a spectroscopic label.
• Academic & Industrial R&D: A fundamental reagent for methodological studies in organic synthesis and process chemistry.

Basic Information

Product Name	2-Amino-2-(3-Bromo-4-Methoxyphenyl)Acetic Acid
CAS No.	1218526-50-1
Molecular Formula	C9H10BrNO3
Molecular Weight	260.09 g/mol
Synonyms	(3-Bromo-4-methoxyphenyl)glycine; 2-Amino-2-(3-bromo-4-methoxyphenyl)ethanoic acid; α-Amino-(3-bromo-4-methoxyphenyl)acetic acid; 3-Bromo-4-methoxy-DL-phenylglycine; DL-3-Bromo-4-methoxyphenylglycine; Bromomethoxyphenylglycine; Bmpg-OH
EINECS	Contact for details

Quality Control

Our production of 2-Amino-2-(3-Bromo-4-Methoxyphenyl)Acetic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, chiral purity (if applicable), and impurity profiles are provided and can be tailored to meet specific customer requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.