Description

2-Azaspiro[4.5]Decane, 8-Methyl- is a specialized spirocyclic amine building block of significant interest in advanced organic synthesis. Its unique constrained spirocyclic structure makes it a valuable intermediate for constructing complex molecular architectures with potential for modulating biological activity and physical properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the spirocyclic moiety can enhance stability and efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Chemical Biology Probes: Employed in the design of molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects.

Basic Information

Item	Detail
Product Name	2-Azaspiro[4.5]Decane, 8-Methyl-
CAS No.	1217862-26-4
Molecular Formula	C10H19N
Molecular Weight	153.27 g/mol
Synonyms	8-Methyl-2-azaspiro[4.5]decane; 2-Azaspiro[4.5]decane, 8-methyl-; 8-Methyl-2-azaspiro[4.5]decan; 8-Methyl-2-aza-spiro[4.5]decane; 8-Methyl-2-azaspiro[4,5]decane; 8-Methyl-2-azaspiro(4.5)decane; 1217862-26-4
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Production follows cGMP principles where applicable, and each batch is analyzed using advanced techniques including GC, HPLC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.