Description

(2R,3R)-3-Amino-2-Hydroxy-3-(3,5-Dimethoxy-Phenyl)-Propionic Acid is a high-purity, non-proteinogenic amino acid derivative characterized by its specific stereochemistry and functional groups. This compound matters as a sophisticated chiral building block, enabling the synthesis of complex molecules with precise three-dimensional structures. It is primarily needed by pharmaceutical and biotechnology research organizations for applications in drug discovery, particularly in the development of enzyme inhibitors, peptide mimetics, and other bioactive agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs).
• Peptidomimetic Research: Used to construct constrained peptide analogs and mimetics to enhance metabolic stability and bioavailability.
• Enzyme Inhibitor Design: Serves as a core structure in the design of potent and selective inhibitors for various therapeutic targets.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes to study biological pathways and protein function.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in stereoselective synthetic routes.
• Academic & Contract Research: Employed in university and CRO laboratories for fundamental research in medicinal chemistry and organic synthesis.

Basic Information

Product Name	(2R,3R)-3-Amino-2-Hydroxy-3-(3,5-Dimethoxy-Phenyl)-Propionic Acid
CAS No.	1217726-90-3
Molecular Formula	C11H15NO5
Molecular Weight	241.24 g/mol
Synonyms	(2R,3R)-3-Amino-2-hydroxy-3-(3,5-dimethoxyphenyl)propanoic acid; (2R,3R)-AHDPA; 3-Amino-2-hydroxy-3-(3,5-dimethoxyphenyl)propionic acid (2R,3R)-isomer; β-Amino-β-(3,5-dimethoxyphenyl)-D-serine; (2R,3R)-3-Amino-2-hydroxy-3-(3,5-dimethoxyphenyl)propionic acid; (2R,3R)-AHDMPP; D-erythro-3-Amino-2-hydroxy-3-(3,5-dimethoxyphenyl)propionic acid
EINECS	Contact for details

Quality Control

Our (2R,3R)-3-Amino-2-Hydroxy-3-(3,5-Dimethoxy-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and identity confirmation by spectroscopic methods, to ensure compliance with research-grade standards. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.