Description

Boc-(S)-2-Methoxy-Phenylglycine is a high-purity, non-natural amino acid derivative featuring a tert-butoxycarbonyl (Boc) protecting group and a chiral center. This compound is a critical chiral building block for the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of active pharmaceutical ingredients (APIs), peptide-based therapeutics, and advanced chemical intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of peptide-based drugs and novel APIs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce methoxy-phenylglycine residues with defined (S)-configuration.
• Protease Inhibitor Development: Serves as a core structural component in the design and synthesis of enzyme inhibitors.
• Chemical Biology Research: Employed in the study of protein-protein interactions and the creation of custom peptide libraries.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in stereoselective organic transformations.
• Fine Chemical Manufacturing: Used for the custom synthesis of specialized, high-value organic compounds for various industries.

Basic Information

Product Name	Boc-(S)-2-Methoxy-Phenylglycine
CAS No.	1217710-00-3
Molecular Formula	C₁₄H₁₉NO₅
Molecular Weight	281.30 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)amino)-2-(2-methoxyphenyl)acetic acid; N-Boc-O-methyl-L-tyrosine; N-(tert-Butoxycarbonyl)-2-methoxy-L-phenylglycine; Boc-2-MeO-Phe-OH; Boc-L-2-Methoxyphenylglycine; (S)-N-Boc-2-methoxyphenylglycine; Boc-(S)-2-Methoxy-α-phenylglycine
EINECS	Contact for details

Quality Control

Our Boc-(S)-2-Methoxy-Phenylglycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.