Description

(2R)-2-(3-Bromophenyl)Pyrrolidine is a high-purity chiral pyrrolidine derivative, a crucial building block in modern asymmetric synthesis and pharmaceutical research. Its value lies in its defined stereochemistry and functionalized aromatic ring, which are essential for constructing complex molecules with high enantiomeric purity. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug candidates.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands used in transition metal catalysis to create enantiomerically pure compounds.
• Agrochemical Research: Used in the discovery and synthesis of new chiral pesticides and herbicides where specific stereochemistry impacts biological activity.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, flavors, fragrances, and other specialty chemicals requiring precise stereocontrol.
• Academic & Institutional Research: A valuable reagent for methodological studies in organic chemistry, focusing on new C-C and C-N bond-forming reactions.

Basic Information

Product Name	(2R)-2-(3-Bromophenyl)Pyrrolidine
CAS No.	1217632-62-6
Molecular Formula	C10H12BrN
Molecular Weight	226.11 g/mol
Synonyms	(R)-2-(3-Bromophenyl)pyrrolidine; (2R)-2-(3-Bromophenyl)-1-azacyclopentane; (R)-3-Bromo-α-(pyrrolidin-2-yl)benzene; 1-[(R)-Pyrrolidin-2-yl]-3-bromobenzene; (R)-2-(3-Bromophenyl)tetrahydropyrrole; (R)-3-Bromophenylpyrrolidine; (2R)-2-(3-Bromophenyl)azacyclopentane
EINECS	Contact for details

Quality Control

Our (2R)-2-(3-Bromophenyl)Pyrrolidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and enantiomeric excess meet the high standards required for research and development. Certificates of Analysis (COA) detailing results from chiral HPLC, NMR, and other relevant tests are provided to guarantee reliable and reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider sealing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.