Description

(3Ar,7As)-5-(Benzyloxycarbonyl)-2-(tert-Butoxycarbonyl)Octahydro-1H-Pyrrolo[3,4-C]Pyridine-7A-Carboxylic Acid is a sophisticated, high-purity chemical intermediate designed for advanced synthetic applications. This compound is critical for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research and development teams in the pharmaceutical and biotechnology sectors, where precise chemical building blocks are essential for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates, particularly those targeting the central nervous system.
• Peptidomimetic Chemistry: Used to introduce constrained, bicyclic proline-like structures into peptide backbones to enhance metabolic stability and bioavailability.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing focused libraries in structure-activity relationship (SAR) studies.
• Process Development: Employed in the scale-up and optimization of synthetic routes for new chemical entities (NCEs) under GMP conditions.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or template in stereoselective transformations to create enantiomerically pure compounds.
• Contract Research & Manufacturing (CRMO): Supplied to organizations specializing in custom synthesis and development services for the life sciences industry.

Basic Information

Product Name	(3Ar,7As)-5-(Benzyloxycarbonyl)-2-(tert-Butoxycarbonyl)Octahydro-1H-Pyrrolo[3,4-C]Pyridine-7A-Carboxylic Acid
CAS No.	1217630-99-3
Molecular Formula	C21H28N2O6
Molecular Weight	404.46 g/mol
Synonyms	(3aR,7aS)-5-[(Benzyloxy)carbonyl]-2-[(tert-butoxy)carbonyl]octahydro-1H-pyrrolo[3,4-c]pyridine-7a-carboxylic acid; (3aR,7aS)-2-(tert-Butoxycarbonyl)-5-(benzyloxycarbonyl)octahydro-1H-pyrrolo[3,4-c]pyridine-7a-carboxylic Acid; 1H-Pyrrolo[3,4-c]pyridine-7a-carboxylic acid, octahydro-5-[(phenylmethoxy)carbonyl]-2-[(1,1-dimethylethoxy)carbonyl]-, (3aR,7aS)-; Z-2-Boc-Octahydro-1H-pyrrolo[3,4-c]pyridine-7a-carboxylic Acid; (3aR,7aS)-2-Boc-5-Cbz-octahydro-1H-pyrrolo[3,4-c]pyridine-7a-carboxylic acid; Bicyclic Proline Derivative; Cbz-Boc Protected Pyrrolopyridine Carboxylic Acid
EINECS	Contact for details

Quality Control

Our (3Ar,7As)-5-(Benzyloxycarbonyl)-2-(tert-Butoxycarbonyl)Octahydro-1H-Pyrrolo[3,4-C]Pyridine-7A-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.