Description

(S)-Benzyl 2-Ethylpiperazine-1-Carboxylate Hydrochloride is a high-purity chiral piperazine derivative, serving as a critical building block in modern pharmaceutical synthesis. Its value lies in providing a stereochemically defined scaffold essential for developing active pharmaceutical ingredients (APIs) with targeted biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in areas requiring complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and antiviral applications.
• API Synthesis: Used in the multi-step synthesis of complex active pharmaceutical ingredients that require the (S)-2-ethylpiperazine moiety.
• Asymmetric Catalysis Research: Serves as a ligand precursor or a chiral auxiliary in the development of new catalytic systems.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Process Chemistry: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	(S)-Benzyl 2-Ethylpiperazine-1-Carboxylate Hydrochloride
CAS No.	1217612-78-6
Molecular Formula	C14H21ClN2O2
Molecular Weight	284.78 g/mol
Synonyms	Benzyl (2S)-2-ethylpiperazine-1-carboxylate hydrochloride; (S)-1-(Benzyloxycarbonyl)-2-ethylpiperazine hydrochloride; (S)-Cbz-2-ethylpiperazine HCl; (S)-2-Ethyl-1-carbobenzoxypiperazine hydrochloride; (S)-1-CBZ-2-ethylpiperazine hydrochloride; (S)-N-Carbobenzoxy-2-ethylpiperazine hydrochloride; (2S)-2-Ethylpiperazine-1-carboxylic acid benzyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-Benzyl 2-Ethylpiperazine-1-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with stringent pharmaceutical-grade standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.