Description

(R)-1-(2,3-Difluoro-4-Methylphenyl)Ethanamine Hydrochloride is a high-purity chiral amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a defined stereocenter and functional handle for constructing complex molecules with high enantiomeric purity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental profile.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands and catalysts used in stereoselective transformations.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.
• Fine Chemical Production: Employed in the multi-step synthesis of other high-value, fluorinated specialty chemicals.

Basic Information

Product Name	(R)-1-(2,3-Difluoro-4-Methylphenyl)Ethanamine Hydrochloride
CAS No.	1217477-52-5
Molecular Formula	C9H11F2N·HCl
Molecular Weight	207.65 g/mol (Free base: 171.19 g/mol)
Synonyms	(R)-1-(2,3-Difluoro-4-methylphenyl)ethan-1-amine hydrochloride; (R)-α-Methyl-2,3-difluoro-4-methylbenzylamine hydrochloride; (R)-1-(2,3-Difluoro-p-tolyl)ethylamine hydrochloride; (R)-2,3-Difluoro-4-methyl-α-methylbenzylamine hydrochloride; (R)-1-(2,3-Difluoro-4-methylphenyl)ethylamine HCl; (R)-1-(2,3-Difluoro-4-methylphenyl)ethanamine HCl; (R)-1-(2,3-Difluoro-4-methylphenyl)ethylammonium chloride
EINECS	Contact for details

Quality Control

Our (R)-1-(2,3-Difluoro-4-Methylphenyl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.