Description

(R)-1-(2-Fluoro-5-Methylphenyl)Ethanamine Hydrochloride is a high-purity chiral amine building block essential for advanced pharmaceutical synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs), particularly for targeted therapies requiring specific stereochemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the creation of novel drug candidates, especially in areas like oncology and neurology.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Used as a building block for constructing complex molecules with defined stereocenters in medicinal chemistry.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective transformations.
• Preclinical Research: Employed in the synthesis of compounds for biological screening and pharmacological studies.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant scale for new drug candidates.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	(R)-1-(2-Fluoro-5-Methylphenyl)Ethanamine Hydrochloride
CAS No.	1217465-66-1
Molecular Formula	C9H13ClFN
Molecular Weight	189.66 g/mol
Synonyms	(R)-1-(2-Fluoro-5-methylphenyl)ethan-1-amine hydrochloride; (R)-α-Methyl-2-fluoro-5-methylbenzylamine hydrochloride; (R)-1-(2-Fluoro-5-methylphenyl)ethylamine HCl; (R)-2-Fluoro-5-methyl-α-methylbenzylamine hydrochloride; (R)-1-(2-Fluoro-5-tolyl)ethanamine hydrochloride; (R)-1-Aminoethyl-2-fluoro-5-methylbenzene hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(2-Fluoro-5-Methylphenyl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.