Description

(1R)-1-(5-Chloro-2-Fluorophenyl)Ethylamine-Hcl CAS NO 1217464-96-4 is a high-purity chiral amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined intermediate essential for creating complex molecules with specific biological activity. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and other specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides and herbicides where specific stereochemistry is required for efficacy.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for high-value, low-volume specialty chemicals.
• Academic and Industrial Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Item	Detail
Product Name	(1R)-1-(5-Chloro-2-Fluorophenyl)Ethylamine Hydrochloride
CAS No.	1217464-96-4
Molecular Formula	C8H10Cl2FN
Molecular Weight	210.08 g/mol
Synonyms	(1R)-1-(5-Chloro-2-fluorophenyl)ethan-1-amine hydrochloride; (R)-1-(5-Chloro-2-fluorophenyl)ethylamine hydrochloride; (R)-α-Methyl-5-chloro-2-fluorobenzylamine hydrochloride; 5-Chloro-2-fluoro-(R)-α-methylbenzylamine HCl; (1R)-1-(5-Chloro-2-fluorophenyl)ethanamine hydrochloride; UNII-Contact for details; Benzeneethanamine, 5-chloro-2-fluoro-α-methyl-, (αR)-, hydrochloride
EINECS	Contact for details

Quality Control

Our production of (1R)-1-(5-Chloro-2-Fluorophenyl)Ethylamine Hydrochloride adheres to stringent quality management systems, ensuring batch-to-batch consistency and high purity suitable for research and cGMP manufacturing. All materials are fully characterized by HPLC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.